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A De Filippis Selected Research

3-O-methylfunicone

10/20113-O-methylfunicone, from Penicillium pinophilum, is a selective inhibitor of breast cancer stem cells.
4/20103-O-Methylfunicone, a metabolite produced by Penicillium pinophilum, modulates ERK1/2 activity, affecting cell motility of human mesothelioma cells.
8/20093-O-methylfunicone, a metabolite of Penicillium pinophilum, inhibits proliferation of human melanoma cells by causing G(2) + M arrest and inducing apoptosis.

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A De Filippis Research Topics

Disease

2Neoplasms (Cancer)
10/2011 - 04/2010
1Infections
01/2015
1Craniosynostoses (Craniosynostosis)
08/2014
1Acrocephalosyndactylia (Apert Syndrome)
08/2014
1Inflammation (Inflammations)
08/2012
1Psoriasis (Pustulosis Palmaris et Plantaris)
08/2012
1Pemphigus (Pemphigus Vulgaris)
04/2012
1Breast Neoplasms (Breast Cancer)
10/2011
1Malignant Mesothelioma
04/2010
1Mesothelioma
04/2010
1Neoplasm Metastasis (Metastasis)
08/2009
1Melanoma (Melanoma, Malignant)
08/2009

Drug/Important Bio-Agent (IBA)

33-O-methylfuniconeIBA
10/2011 - 08/2009
2OsteopontinIBA
08/2012 - 04/2012
2CytokinesIBA
08/2012 - 04/2012
2Proteins (Proteins, Gene)FDA Link
04/2012 - 04/2010
1Type 2 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 2)IBA
08/2014
1Collagenases (Collagenase)FDA Link
08/2012
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
08/2012
1Glycoproteins (Glycoprotein)IBA
08/2012
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2012
1AntibodiesIBA
04/2012
1integrin alphaVbeta5IBA
04/2010
1Pharmaceutical PreparationsIBA
04/2010
1Messenger RNA (mRNA)IBA
04/2010

Therapy/Procedure

2Therapeutics
08/2012 - 04/2010
1Antibiotic Prophylaxis
01/2015
1Drug Therapy (Chemotherapy)
10/2011
1Radiotherapy
10/2011